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Updated: Sep 8, 2025

Ion Mobility-Mass Spectrometry Techniques for Determining the Structure and Mechanisms of Metal Ion Recognition and Redox Activity of Metal Binding Oligopeptides
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Ion Mobility-Mass Spectrometry Techniques for Determining the Structure and Mechanisms of Metal Ion Recognition and Redox Activity of Metal Binding Oligopeptides

Published on: September 7, 2019

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アスペルギルス・フミガトゥスメタロチオニンCmtAは,モノチオールグルタレドキシンGrxDから [2Fe-2S]クラスタを結合し,受け取る

David Eap1, Megan Ugro1, Timothy W Sherrier1

  • 1Department of Chemistry and Biochemistry, University of South Carolina, Columbia, South Carolina 29208, United States.

Journal of the American Chemical Society
|September 5, 2025
PubMed
まとめ

この研究は,アスペルギルス・フミガトゥスのタンパク質GrxDとCmtAが,真菌の毒性を管理するためにどのように相互作用するかを明らかにしています. GrxDはCmtAに鉄硫黄のクラスターを供給し,鉄の恒常状態に影響を与えます.

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