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Updated: Sep 8, 2025

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production
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Published on: March 2, 2014

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アヒルの疫病ウイルスのICP27タンパク質は,DNAとRNAセンシング経路の二重ターゲティングによってIFN-βの生成を抑制する

Mengya Zhang1, Yumei He1, Fengchen Jin1

  • 1Avian Disease Research Center, College of Veterinary Medicine of Sichuan Agricultural University, Wenjiang, China.

Veterinary microbiology
|September 5, 2025
PubMed
まとめ

アヒルの疫病ウイルス (DPV) は,DNAとRNAの検知経路の両方をブロックすることによって宿主免疫を回避するためにICP27を使用します. ICP27を除去すると 抗ウイルス遺伝子の発現が増加し 重要な免疫回避戦略が明らかになります

キーワード:
CGAS-STING/RIG-Iシグナリングアヒルの疫病ウイルス (DPV)ICP27 についてIFN-β生まれつきの免疫回避

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