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大人の腎臓移植後の早期手術合併症: 系統的レビュー

  • 0Urological Research Unit, Centre for Cancer and Organ Diseases, Copenhagen University Hospital - Rigshospitalet, Ole Maaløes Vej 24, 2(nd) floor, 2200 Copenhagen, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, Denmark.

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まとめ

この要約は機械生成です。

腎臓移植の短期的な合併症率は高く,全体の割合は36~41%です. 高いBMIや受容者の年齢などの リスク要因を特定することは この複雑な手順の 結果を改善するために 極めて重要です

科学分野

  • 腎臓科
  • 手術腫瘍学
  • 移植医学

背景

  • 腎臓移植は 末期腎疾患の救命処置です
  • 短期的な外科的合併症は患者の回復と移植の生存に重大な影響を及ぼします.
  • 合併症の標準化された報告は,結果の評価と品質の改善に不可欠です.

研究 の 目的

  • 腎臓移植後の短期 (90日以内) の外科的合併症の量化と特徴づけ
  • これらの合併症に関連する潜在的な危険因子を特定する.
  • 腎臓移植の合併症に関する既存の証拠の質と異質性を評価する.

主な方法

  • PRISMAのガイドラインに沿った体系的なレビュー.
  • 移植後90日以内に手術/手術後の合併症を報告した研究を含む.
  • ニューカッスル・オタワスケール (NOS) とマーティン基準を用いた品質評価

主要な成果

  • 1654件から30件を対象とした.
  • 合併症の総比率は41% (30日) と36% (90日) であった.
  • 再手術の比率は13% (30日) と17% (90日) であった.
  • 重度の合併症の比率は19% (30日) と24% (90日) であった.
  • 高いBMI,受容者の年齢,性別を潜在的な危険因子として特定した.
  • 証拠の質は (悪いから良いまで) 変化し,マーティンの基準の平均は7であった.

結論

  • 腎臓移植はリスクの高い手術で 短期的に重大な合併症が発生します
  • 合併症の報告の多様性は,結果の比較と介入の影響評価を妨げています.
  • 手術結果を改善し,比較効果の研究を容易にするため,報告のさらなる標準化が必要である.

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