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Updated: Sep 8, 2025

Flow Cytometric Characterization of Murine B Cell Development
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B細胞のジレンマ 多様性か忠誠性か

Maria Berruezo-Llacuna1, Eleni Kabrani2, Michela Di Virgilio3

  • 1Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Laboratory of Genome Diversification & Integrity, Berlin, Germany.

DNA repair
|September 5, 2025
PubMed
まとめ

B細胞は免疫のためのDNA改造を使用して抗体遺伝子を多様化しますが,ゲノム不安定性のリスクに直面します. 免疫受容体の多様化と DNA修復のバランスをとって ゲノムの完全性を保ちます

キーワード:
B リンパ球クラス・スイッチの再組み合わせ誤りのないDNA修復プログラムされたDNA損傷ソマティック・ハイパーミューテーションV(D) J 再結合

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