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Updated: Sep 8, 2025

Cancer-Associated Fibroblasts from Mouse Mammary Tumors as Tools for Molecular and Computational Studies
09:01

Cancer-Associated Fibroblasts from Mouse Mammary Tumors as Tools for Molecular and Computational Studies

Published on: July 3, 2025

242

乳がんの進行を解読するための単細胞ゲノムとトランスクリプトームの凝集

Kaile Wang1, Rui Ye2, Shanshan Bai3

  • 1Department of Systems Biology, UT MD Anderson Cancer Center, Houston, TX 77030, USA; State Key Laboratory of RNA Innovation, Science and Engineering, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai 200031, China.

Cell
|September 5, 2025
PubMed
まとめ

wellDR-seqという 新しい方法は 乳がんの起源と遺伝子発現のリンクを明らかにするために 何千もの単細胞をプロファイルします この技術は 癌の理解を深めるため 単細胞における複雑な遺伝子型-フェノタイプ関係を明らかにします

キーワード:
DNAコピー番号アヌプロイド乳がんゲノミクス乳がんの進行遺伝子用量効果単細胞DNAとRNAのシーケンシング単細胞マルチオミクス単細胞シーケンシング腫瘍の進化井戸DR-seq

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