健康で,麻酔され,自発的に呼吸する犬の食道圧および心血管機能に対する高フロー鼻酸素療法の影響
Beomkwan Namgoong1, Daeyun Seo1, Seongsoo Lim1
1Veterinary Emergency Medicine, Department of Veterinary Clinical Science, College of Veterinary Medicine, Research Institute for Veterinary Science, Seoul National University, Seoul, South Korea.
American journal of veterinary research
|September 5, 2025
まとめ
犬の高流量鼻酸素療法 (HFNOT) は,心臓血管機能に悪影響を及ぼさずに食道圧を増加させた. この呼吸器のサポートにより 呼吸速度も低下し 麻酔を受けた犬の患者にも 効果が期待できます
科学分野:
- 獣医麻酔科
- 呼吸器の生理学
- 心血管モニタリング
背景:
- 高フロー鼻酸素療法 (HFNOT) は,人体医学でますます使用されています.
- 犬における胸内圧および心血管/呼吸器のパラメータに対する効果は十分に理解されていません.
- 食道圧は胸内圧の代わりとして機能する.
研究 の 目的:
- 健康な犬の食道圧に対するHFNOTの影響を評価する.
- HFNOTの間,心臓血管と呼吸器系への影響を評価する.
- 麻酔で自発的に呼吸する犬におけるHFNOTの臨床的関連性を決定する.
主な方法:
- 6匹の健康なビーグル犬をアルファキサロン麻酔で対象とした前向きなランダム化試験.
- HFNOTは,ベースラインと回復の測定で1および2L/ kg/ minで投与されました.
- 食道圧,心血管のパラメータ (心臓指数,平均動脈圧),呼吸器のパラメータ (呼吸率,血液ガス) を記録した.
主要な成果:
- HFNOTで食道圧は流れに依存して上昇した.
- 平均動脈圧と心臓指数は安定し,MAPは2L/ kg/ minで有意に上昇した.
- 呼吸速度は2L/ kg/ minで有意に低下したが,動脈血中ガス値は変化しなかった.
結論:
- HFNOTは,健康な麻酔犬の食道圧力を効果的に増加させ,胸内圧力の変化を示します.
- これらの圧力変化は心臓血管に重大な影響を与えない状態で起こりました.
- HFNOTは,血液ガス交換に悪影響を及ぼさずに呼吸速度を低下させ,この集団における安全な使用を示唆しています.
関連する概念動画
01:16Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure
316
Oxygen therapy has emerged as a significant tool in enhancing the quality of life for patients suffering from pulmonary arterial hypertension (PAH). While this therapy has principally been studied on patients with significant hypoxemia, this therapeutic approach helps prevent potential organ damage and can be administered in the comfort of one's home.
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue,...
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue,...
316
01:29Administering Oxygen by Nasal Cannula
997
Oxygen therapy is critical to patient care, especially for those struggling with respiratory issues. This intervention increases the oxygen concentration in the lungs, enhancing the amount of oxygen transported to the body's tissues. One standard method of delivering supplemental oxygen is through a nasal cannula, a non-invasive device that provides low to medium oxygen concentrations.
Nasal Cannulas
A nasal cannula is a lightweight tube split into two prongs placed in the nostrils,...
Nasal Cannulas
A nasal cannula is a lightweight tube split into two prongs placed in the nostrils,...
997
01:23Physiological Control of Respiration
3.2K
Introduction
Breathing, a seemingly passive process, is regulated by the respiratory center in the brainstem. This center coordinates the involuntary control of respirations, which means it occurs without conscious effort, ensuring a smooth and uninterrupted pattern.
Regulation of Ventilation
The body maintains ventilation by monitoring levels of carbon dioxide (CO2), oxygen (O2), and hydrogen ion concentration (pH) in the arterial blood. Among these factors, the level of CO2 plays a crucial...
Breathing, a seemingly passive process, is regulated by the respiratory center in the brainstem. This center coordinates the involuntary control of respirations, which means it occurs without conscious effort, ensuring a smooth and uninterrupted pattern.
Regulation of Ventilation
The body maintains ventilation by monitoring levels of carbon dioxide (CO2), oxygen (O2), and hydrogen ion concentration (pH) in the arterial blood. Among these factors, the level of CO2 plays a crucial...
3.2K
01:26Oxygen Delivering System I: Nasal Cannula and Face Mask
578
The human body requires oxygen to function, and when the natural process of respiration is hindered, external devices, including the following, are needed to help deliver this vital gas.
Nasal Cannula
A nasal cannula is a lightweight tube split at one end into two prongs and placed in the nostrils. It is typically used to deliver low to medium levels of oxygen.
Suggested flow rate: The suggested flow rate for a nasal cannula typically ranges between 1 and 6 L/min.
Oxygen percentage setting:...
Nasal Cannula
A nasal cannula is a lightweight tube split at one end into two prongs and placed in the nostrils. It is typically used to deliver low to medium levels of oxygen.
Suggested flow rate: The suggested flow rate for a nasal cannula typically ranges between 1 and 6 L/min.
Oxygen percentage setting:...
578
01:19Respiratory Assessment: Purpose and Indications
1.2K
Respiratory assessment is a cornerstone of nursing assessments, crucial for the early detection of patient deterioration. This evaluation transcends routine procedures, representing a critical skill nurses must master to ensure optimal patient care.
Objectives and Importance:
The primary goal of respiratory assessment is to evaluate patients at early risk of clinical deterioration. Since respiratory distress often precedes other signs of declining health, breathing patterns and sounds become a...
Objectives and Importance:
The primary goal of respiratory assessment is to evaluate patients at early risk of clinical deterioration. Since respiratory distress often precedes other signs of declining health, breathing patterns and sounds become a...
1.2K
01:22Cardiopulmonary Resuscitation II: ACLS Airway Management
86
Airway management is a key skill in emergency and critical care settings, as maintaining a clear airway is essential for adequate oxygenation and ventilation.Head Tilt-Chin Lift TechniqueThe head tilt-chin lift maneuver is an essential technique primarily used in patients without suspected cervical spine injuries. To perform this maneuver, one hand is placed on the patient’s forehead, and gentle pressure is applied backward to tilt the head. The fingertips of the other hand are positioned...
86