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Updated: Sep 8, 2025

Biosensor-based High Throughput Biopanning and Bioinformatics Analysis Strategy for the Global Validation of Drug-protein Interactions
08:31

Biosensor-based High Throughput Biopanning and Bioinformatics Analysis Strategy for the Global Validation of Drug-protein Interactions

Published on: December 1, 2020

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Ca2+/カルモジュリン依存タンパク質キナーゼII (CaMKII) 標的薬の発見:課題と戦略

Xinmiao Tian1, Xianghui Wang1, Sichong Chen1

  • 1Department of Pharmaceutical Toxicology, School of Pharmacy, China Medical University, Shenyang, 110122, China.

Ageing research reviews
|September 5, 2025
PubMed
まとめ

カルシウム (Ca2+) /カルモジュリン (CaM) 依存タンパク質キナーゼII (CaMKII) は,年齢関連の疾患の有望な標的である. PROTACsや遺伝子編集のような新しい戦略は,効果的なCaMKII阻害剤の開発に希望を与えます.

キーワード:
歳をとるCaMKII阻害剤アイソフォーム生理学と病気ターゲット

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