関連する実験動画

Updated: Sep 8, 2025

Evaluating Vascular Hyperpermeability-inducing Agents in the Skin with the Miles Assay
08:43

Evaluating Vascular Hyperpermeability-inducing Agents in the Skin with the Miles Assay

Published on: June 19, 2018

15.1K

ヒスタミンは,ヒスタミンH1受容体-細胞外調節タンパク質キナーゼ1/2-サイクリンD1/サイクリン依存キナーゼ4/6軸経由で血管内皮細胞増殖を誘導する

Hidenori Wake1, Omer Faruk Hatipoglu1, Takashi Nishinaka1

  • 1Department of Pharmacology, Kindai University, Faculty of Medicine, Osaka-Sayama, 589-8511, Japan.

Microvascular research
|September 5, 2025
PubMed
まとめ

ヒスタミンはH1受容体を通して内皮細胞の増殖を刺激し,細胞サイクル進行を促進するシグナリングカスケードを活性化します. この発見は 創傷治癒や癌治療の 潜在的治療目標を提供します

キーワード:
CDK4/ 6 阻害剤細胞サイクルヒスタミンヒスタミンH1受容体血管内皮細胞の増殖

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