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妊娠期の乳牛の乳腺発育に対する乳内感染症の影響
M X S Oliveira1, C S Gammariello2, P H Baker2
1Department of Animal Sciences, Ohio Agricultural Research and Development Center, The Ohio State University, Wooster, OH 44691; Department of Animal Sciences, The Ohio State University, Columbus, OH 43210.
Journal of dairy science
|September 5, 2025
まとめ
妊娠中の雌牛の乳腺内感染は乳腺組織を損傷し,特に妊娠後期に発生します. Staphylococcus aureusは,乳分泌能力に潜在的に影響を与える,光の領域を減少させる.
科学分野:
- 獣医学
- 動物科学
- 生殖生物学
背景:
- 乳腺内感染症 (IMI) は,妊娠していない牛の乳腺組織構造を破壊することが知られている.
- 妊娠中の乳腺の発達,特に乳牛の乳腺の発達への IMI の影響は,まだ十分に理解されていません.
- これらの効果を理解することは,乳腺の健康管理と妊娠中の家畜の生産能力の確保に不可欠です.
研究 の 目的:
- 妊娠期の乳腺内感染 (IMI) が妊娠中の乳牛の乳腺発育に及ぼす影響を評価する.
- Staphylococcus aureusの挑戦が乳腺組織形態測定と免疫細胞の浸透にどのように影響するかを調査する.
主な方法:
- 妊娠期 (約5.75ヶ月,6.75ヶ月,7.75ヶ月) を3つに分けて21頭のホルシュタイン雌牛を使用した.
- 反対側の四分の一のペアの設計は,四分の一を塩水 (コントロール) で,もう一つをStaphylococcus aureus (チャレンジ) で注入することを含む.
- 21日後に乳腺分泌物と組織サンプルを採取し,体細胞数,免疫細胞浸透,組織形態測定を分析した.
主要な成果:
- テストされた四半期は,対照群と比較して体細胞数と中性粒子の割合が増加した.
- IMIは免疫細胞の浸透を誘導し,乳腺組織における分泌のスコアを低下させた.
- 妊娠後の段階では脂肪組織が減少し,葉の領域が大きくなった. 8. 5ヶ月で挑戦された四半期は,顕著に小さな光領域を示した.
結論:
- 乳腺内感染症は,妊娠中の雌牛の乳腺組織に重大な損傷を与え,妊娠後期にはより顕著に発現します.
- IMIによって引き起こされる構造の変化は,異なる乳腺領域と妊娠年齢によって異なります.
- 感染した腺の乳の蓄積と分泌能力に対する潜在的なリスクを示唆しています.
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