エクアドル の 中空 の 樹木 で グアノ に 曝露 さ れ た 後 の 急性 肺 ヒストプラズモシス の 発生
Andrea Giacomelli1, Cristina Gervasoni2, Giacomo Casalini2
1Department of Biomedical and Clinical Sciences, Università degli Studi di Milano, 20122, Milan, Italy; III Infectious Diseases Unit, ASST Fatebenefratelli Sacco, Luigi Sacco Hospital, 20157, Milan, Italy.
Travel medicine and infectious disease
|September 5, 2025
まとめ
急性肺ヒストプラズモシスは,エクアドルのアマゾンを訪れる免疫力のある旅行者に影響を及ぼします. このケースシリーズは 症状が変化し 肺の穴が開く頻度が 治療後でさえも少ないことを強調しています
科学分野:
- 感染症
- 菌類学
- 肺科
背景:
- ヒストプラズモスの発生率は,流行地域以外の旅行者において増加しています.
- 旅行習慣の変化は 曝露のリスクを高めます
- 免疫能力のある個人がますます影響を受けています.
研究 の 目的:
- 旅行者の急性肺組織形成症の集団を記述する.
- 臨床的変異性と診断上の課題を強調する
- アマゾン地域から帰還する旅行者のフォローアップの重要性を強調する.
主な方法:
- 急性肺ヒストプラズモ症の患者5人のケースシリーズ
- 臨床的表象,診断検査,イメージングの遡及分析
- エクアドルのアマゾンの空洞の木のグアノを介して感染したと考えられる.
主要な成果:
- 旅行後16~23日に 5人の若い成人がヒストプラズモシスを発症した.
- 発熱,関節痛,胃腸障害,リンパ腺病など,初期症状は様々でした.
- 胸部CTでは,イトラコナゾール治療にもかかわらず3人の患者で二面的な結節が現れた.
結論:
- ヒストプラズモスは臨床的に有意な変化を示します.
- 急性疾患の肺腔動は稀だが,臨床的に有意である.
- アマゾンのような流行地域から 戻ってくる旅行者には 厳格なフォローアップが不可欠です
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