代謝症候群とその構成要素が肥満の子供および青少年における肺機能および機能能力に及ぼす影響
Lertluksana Limkul1, Kanokporn Udomittipong2, Pawinee Charoensittisup1
1Division of Pulmonology, Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wanglang Road, Bangkok Noi, Bangkok, 10700, Thailand.
European journal of pediatrics
|September 5, 2025
まとめ
肥満の子供や青年の代謝症候群 (MetS) は,機能能力を著しく低下させ,6分歩行テスト (6- MWT) のパフォーマンスに影響します. 腹周りの大きさと 血糖値の上昇は この減少を予測する重要な要因です
科学分野:
- 小児内分泌学
- 肺医学
- 代謝 健康
背景:
- 肥満はメタボリックシンドローム (MetS) と関連した世界的な健康問題です.
- 肥満児の肺機能に対するMetSとその成分の影響はよく定義されていません.
研究 の 目的:
- 肥満の小児の肺機能との関係を調査する.
- 肺の症状と運動能力に悪影響を及ぼす特定のメトセラピスト成分を特定する.
主な方法:
- 肥満児と青少年 (7~18歳) は,人体測定と代謝評価のために登録されました.
- スピロメトリーと6分歩行テスト (6-MWT) を実施.
- 参加者をMetSまたは非MetSグループに分類し,回帰分析を行った.
主要な成果:
- MetSを患った参加者は,MetSを患っていない人と比較して,6-MWT距離のz-スコアが有意に低かった.
- 群の間でスピロメトリックパラメータの有意な差異は観察されなかった.
- 腹周長と高血糖 (> 100 mg/ dL) は6MWTの減少とFEV1%の減少を予測した.
結論:
- 肥満の子供やMetSの青少年は,機能能力が低下し,6-MWTの性能が低下することが示されています.
- 腹周りの大きさの増加と空腹時の血糖値の上昇は,この集団における機能能力の低下を予測する重要な要因です.
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