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Updated: May 6, 2026

Scanning Electron Microscopy of Macerated Tissue to Visualize the Extracellular Matrix
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METTL3サイレンシングは,m6Aによる心筋梗塞後の心筋線維症を抑制する SMOC2の修正

Yanru He1, Xiaodong Pan1, Zhuyuan Liu1

  • 1Department of Cardiology, Zhongda Hospital Affiliated to Southeast University, Nanjing, China.

Journal of cellular and molecular medicine
|September 6, 2025
PubMed
まとめ

この研究は,METTL3媒介によるm6Aメチル化が,SMOC2 mRNAを安定させ,心臓の機能に影響することで,心筋梗塞後の心筋線維症を促進することを明らかにしています. この経路をターゲットにすることで 心不全の新たな治療戦略が生まれます

キーワード:
METTL3 についてSMOC2について心筋線維症m6A 変更心筋梗塞

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