低用量アトロピンの対応と融合システム
Emily C Woodman-Pieterse1, Rohan P J Hughes1, Shelley Hopkins1
1Centre for Vision and Eye Research, Queensland University of Technology, Brisbane, Queensland, Australia.
まとめ
低用量アトロピンの眼滴は,アコーダクションを大きく乱し,収束の近くで増加します. これは双眼視に影響を及ぼし,適応幅度と融合収束を減少させ,近視の制御に注意深く監視する必要があります.
科学分野:
- 眼科について
- オプトメトリ
- 視覚科学
背景:
- 低用量のアトロピンは近視のコントロールに使用されます.
- 双眼視力システムに対するその包括的な影響は完全に理解されていません.
- 既存の研究は,主にアコモダティブ・アンプリチュードに焦点を当てている.
研究 の 目的:
- 0. 05%のアトロピンの眼滴が,広範囲にわたるアコーダーションとヴァーゲンスのパラメータに及ぼす影響を調査する.
- 成人の近視患者に10日間の期間でこれらの効果を評価する.
- アクモダティブ・アンプリチュードを超えて 詳細な分析を提供するために
主な方法:
- 20人の近視者が参加した ランダム化比較試験です
- 参加者は9日間,毎晩0. 05%のアトロピンまたはプラセボ (0. 9%の塩化ナトリウム) の眼滴を投与された.
- 測定には,適応姿勢,振幅,施設,相対的適応,ヘテロフォリア,融合性,NPC,およびベースラインのAC/A比,第3日および第10日が含まれていました.
主要な成果:
- アトロピン群では,10日目までにアコモダティブレイグが増加し,アコモダティブアンプリチュード,PRA,BAFが減少した.
- ヘテロフォリアの近くはエゾフォリアにシフトし,NFVの断裂と回復点が減少した.
- NPCはアトロピン群で著しく減少し,収束の努力が増加したことを示した.
結論:
- 0. 05%のアトロピンは,住居を大幅に破壊し,10日間で収束に近い増加します.
- 消極的融合が減少したため,食欲症に対抗する能力は低下した.
- 近視の制御のためにアトロピンを使用する子供には,近視と融合貯蔵の密接なモニタリングが推奨されます.
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