関連する実験動画

Updated: Sep 8, 2025

An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis
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An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis

Published on: September 12, 2019

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肝がんに対する免疫チェックポイント阻害剤またはチロシンキナーゼ阻害剤を投与する患者におけるB型肝炎ウイルスの再活性化の比較リスク

Dorothy Cheuk-Yan Yiu1,2, Jimmy Che-To Lai1,2,3,4, Landon Long Chan5

  • 1Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, Hong Kong.

Alimentary pharmacology & therapeutics
|September 6, 2025
PubMed
まとめ

B型肝炎ウイルスの再活性化 (HBVr) のリスクは,抗ウイルス予防療法中に免疫チェックポイント阻害剤 (ICI) を投与している肝がん患者では低い. この研究では,現在または過去にHBV感染した患者で,ICIとチロシンキナーゼ阻害剤 (TKI) の間でHBVrリスクが類似していることが判明しました.

キーワード:
B型肝炎の再活性化肝細胞がん免疫チェックポイント阻害剤タイロシンキナーゼ阻害剤

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