"ウィークエンド・ウォリアー"の運動パターンと発がんのリスク
Rubén López-Bueno1,2,3, Lars Louis Andersen2,4, Laura López-Bueno3
1Department of Physical Medicine and Nursing, University of Zaragoza, Zaragoza, Spain.
Annals of medicine
|September 6, 2025
まとめ
週末に激しい運動をしたり,週中に定期的に運動したりすると,肺がんのリスクも同様に減少しました. しかし,いずれのパターンも他の主要な癌のリスクに影響を与えませんでした.
科学分野:
- 運動科学
- 腫瘍学
- 流行病学
背景:
- 身体活動パターンは様々で,ある人は週末に最も多くの活動 ('週末の戦士') を蓄積し,他の者はそれを均等に拡散します.
- 異なる身体活動分布が 癌のリスクに影響するかを理解することは公衆衛生のガイドラインにとって 極めて重要です
研究 の 目的:
- 身体活動パターンの違いと がん発症のリスクとの関連を調査する.
- "週末の戦士"のパターンと 適度から激しい身体活動 (MVPA) の定期的な,均等に分布したパターンを比較する.
主な方法:
- アクセレロメーターで測定した身体活動を用いた英国バイオバンク研究 (n=80,896) のプロスペクティブコホート分析.
- 参加者を3つのグループに分類する. 週間のMVPAレベルと分布に基づいて,アクティブの週末の戦士,アクティブのレギュラー,および非アクティブ.
- コックス回帰モデルを使用して,身体活動パターンと前立腺がん,乳がん,大腸がん,肺がんの関連性を評価し,関連する共変数を調整した.
主要な成果:
- 活動的な週末の戦士と定期的な活動パターンの両方が 肺がんのリスクと有意に逆の関連性を示しました
- 活発な身体活動パターンと前立腺癌,乳癌,大腸癌の全体的なリスクとの間に有意な関連は見つかりませんでした.
- 週末の戦士と定期的な運動パターンの間で肺がんのリスクの減少は類似していました
結論:
- 1~2日間の中度から激しい身体活動 (MVPA) の蓄積またはより均等な分布は,肺がんのリスクの同様の減少と関連しています.
- 週末の戦士も定期的な運動パターンも 総体,前立腺,乳がん,大腸がんのリスクの減少と関連していません.
- MVPAの介入により,非活動的な個体での癌リスクの軽減をさらに研究すべきです.
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