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Updated: Sep 8, 2025

Parallel Measurement of Circadian Clock Gene Expression and Hormone Secretion in Human Primary Cell Cultures
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Parallel Measurement of Circadian Clock Gene Expression and Hormone Secretion in Human Primary Cell Cultures

Published on: November 11, 2016

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ノビレチンは,クロック調節信号を通して,島β細胞のNpy1r媒介によるインスリン分泌不足を緩和する

Qianru Xiang1,2, Xiao Chen1, Enhui Tang1

  • 1Department of Nutrition and Food Hygiene, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, Guangdong, China.

Molecular nutrition & food research
|September 6, 2025
PubMed
まとめ

ノビレチン (NOB) は,神経ペプチドY1受容体 (Npy1r) を調節し,RORs/ Bmal1- Yap経路を活性化させ,β細胞を保護することによって,II型糖尿病におけるインスリン分泌と高血糖を改善する.

キーワード:
B マル1シルカディアンリズムインスリン分泌小島ニューロペプチドノビレチン2 型糖尿病

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Confocal Imaging of Neuropeptide Y-pHluorin: A Technique to Visualize Insulin Granule Exocytosis in Intact Murine and Human Islets

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