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Updated: Sep 8, 2025

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グリオブラストーマにおけるレジスタンス克服のためのテモゾロミド由来の治療戦略

Hualin Zhang1, Yupeng Li1,2,3

  • 1Department of Chemistry and Biochemistry, The University of Texas at El Paso, El Paso, Texas 79968, United States.

Journal of medicinal chemistry
|September 6, 2025
PubMed
まとめ

グリオブラストーマの治療は,特にMGMT非メチル化症例において,テモゾロミド (TMZ) 耐性で困難に直面する. 研究は,新しいTMZ誘導体と組み合わせを研究し,多形性膠芽細胞腫の生存率を向上させることに焦点を当てています.

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