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Updated: Sep 8, 2025

Isolation and Quantification of Epstein-Barr Virus from the P3HR1 Cell Line
09:14

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DDX3X変異とエプスタイン・バーウイルスは,R回路依存性腫瘍生成を誘発するために協力する

Hua-Man Cai1, Yu-Ran Qiu1, Yun Tan1

  • 1Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Cell reports
|September 6, 2025
PubMed
まとめ

RNAヘリケーズDDX3Xの変異は,先天的な免疫を弱め,エプスタイン・バーウイルス (EBV) のリチック遺伝子BNLF2bを活性化することによって癌を促進します. これはRループの蓄積と ゲノム不安定につながり 新しい治療標的を提示します

キーワード:
CP: がんについてCP:ゲノミクスDDX3XDNA 損傷エプスタイン・バーウイルスRループゲノムの不安定性腫瘍形成合成による死亡率

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