関連する実験動画

Updated: Sep 8, 2025

Light-mediated Reversible Modulation of the Mitogen-activated Protein Kinase Pathway during Cell Differentiation and Xenopus Embryonic Development
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Light-mediated Reversible Modulation of the Mitogen-activated Protein Kinase Pathway during Cell Differentiation and Xenopus Embryonic Development

Published on: June 15, 2017

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ケモゲネティック・チューニングは,細胞運命をプログラムするための最適なMAPKシグナリングを明らかにする

Brittany A Lende-Dorn1, Jane C Atkinson1, Yunbeen Bae1

  • 1Department of Chemical Engineering, MIT, Cambridge, MA 02139, USA.

Cell reports
|September 6, 2025
PubMed
まとめ

ミトゲン活性化タンパク質キナーゼ (MAPK) のシグナルレベルを最適化することは,効率的な細胞命運の再プログラムに不可欠です. 信号が少なすぎると 変換が妨げられ 信号が多すぎると 老化が起こり 治療的な"金髪"ゾーンが 浮き彫りになります

キーワード:
CP: 発達生物学MAPKNgn2 についてRAS について細胞の運命直接変換するp53 について拡散衰えることトランスディフェリエンテーション

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