哺乳期における母乳におけるコレンの濃度と成分:体系的なレビューとメタ解析
Mingjia Yang1,2, Yubo Zhou1,2,3, Shunzhe Wu1,2
1Institute of Reproductive and Child Health, National Health Commission Key Laboratory of Reproductive Health, School of Public Health, Peking University, Beijing, China.
Critical reviews in food science and nutrition
|September 6, 2025
まとめ
適切なコレンの摂取は 乳児の健康に不可欠です ヒトの牛乳のコレンのレベルは 国の経済状況によって変化し コロストラムから成熟した牛乳まで増加します
科学分野:
- 栄養学
- ヒトの授乳
- 幼児 栄養
背景:
- コリンは幼児の健康と発達に不可欠です.
- 母乳のコレンの濃度は 乳児の栄養発育に不可欠です
- 既存の研究では,ヒトの乳中のコレンの濃度に大きな変動があることが示されています.
研究 の 目的:
- 乳中のコレンの濃度を体系的に検討し分析する.
- 牛乳の種類や母体/地域特性を含むコレンのレベルに影響を与える要因を探る.
- 乳幼児の適切なコレンの摂取量に関する推奨事項を定めるためのデータを提供すること.
主な方法:
- 2025年8月までの主要科学データベース (PubMed,Embase,Web of Science,Scopus,CNKI) の体系的な文献検索
- 産後6ヶ月以内に1747人の健康な母親を対象とした17件の研究を含めた.
- トータルコレイン (TC) と水溶性コレイン (WSC) の総合データに3段階メタ分析モデルを適用する.
主要な成果:
- 総コレイン (TC) 濃度は126.2 mg/L (プライマリ分析) と134.2 mg/L (二次分析) と推定されている.
- 水溶性コレイン (WSC) はTCの約83. 3%を占めた.
- コロストラム (71.5 mg/L) から移行期 (152.2 mg/L) と成熟した牛乳 (145.0 mg/L) へのTCの有意な増加
- 国々の経済レベルは,測定方法と地理的地域とともに,TC濃度に大きな影響を与えた.
結論:
- 哺乳期にはコリン濃度がはっきりして コロストラムから成熟した牛乳に増加します
- 経済的要因は母乳のコレンのレベルを決定する上で重要な役割を果たします.
- 発見は,乳児の栄養と配合に関する根拠に基づいたガイドラインを裏付けています.
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