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Updated: Sep 8, 2025

A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones

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ブロンステッド酸触媒による1Hインダゾールのアルキル化

Shiji Xiao1, Zhiyang Wang2, Qin Han2

  • 1School of Petrochemical Engineering, Changzhou University, Changzhou, Jiangsu 213164, P. R. China.

Organic letters
|September 6, 2025
PubMed
まとめ

この研究は,選択的なインダゾールアルキル化のための無金属触媒法を導入し,医薬品化学における以前の課題を克服しました. この新しいアプローチは 肺がんに対する 潜在的な薬剤を効率的に合成します

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