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Updated: Sep 8, 2025

Stability and Structure of Bat Major Histocompatibility Complex Class I with Heterologous β2-Microglobulin
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Stability and Structure of Bat Major Histocompatibility Complex Class I with Heterologous β2-Microglobulin

Published on: March 10, 2021

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HMGB1 B-Box ドメイン アソシエイト タンパク質-ポリエレクトロライト相互作用を促進する

Marten Kagelmacher1,2, Marina Pigaleva1, Ricardo Zarate1

  • 1Institute of Chemistry and Biochemistry, Freie Universität Berlin, 14195 Berlin, Germany.

The journal of physical chemistry. B
|September 6, 2025
PubMed
まとめ

高流動性グループボックス1 (HMGB1) のタンパク質の自己結合は,特にそのBボックス領域を通じて,ヘパリン結合を強化する. このマルチメリゼーションは充電された領域を作り 免疫調節に不可欠なヘパリンのようなポリアニオンとの相互作用を 改善します

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