JMJ720は,米の粒径を調節するH3K9me2デメチラーゼをコードする
Xiaoche Wang1, Zhiwen Yu1, Xiang Li1
1Rice Research Institute of Shenyang Agricultural University, Shenyang, 110 866, China.
The Plant journal : for cell and molecular biology
|September 6, 2025
まとめ
研究者たちは 米粒の大きさを制御する JMJ720 遺伝子を特定しました OsNDB2遺伝子をエピジェネティックに制御することで,米の収穫を改善するための新しい戦略を提供します.
科学分野:
- 植物分子遺伝学
- エピジェネティクス
- 植物の科学
背景:
- 穀物の大きさは,米の収穫に影響を与える重要な要因です.
- 米粒の大きさを 制御する正確な 分子機構は 完全に理解されていません
- エピジェネティック・レギュレーションは植物の発達と特徴の決定に役割を果たします.
研究 の 目的:
- 米粒の大きさの重要な遺伝子調節因子を特定する.
- エピジェネティック経路を通して粒子の大きさを制御する分子機構を明らかにする.
- 米粒のサイズと収穫量を高めるための潜在的な戦略を探求する.
主な方法:
- JMJ720の位置を 特定するために マップベースのクローン
- jmj720変異体について 粒子の大きさのフェノタイプに関する分析
- OsNDB2場所でのH3K9me2レベルを評価するためのヒストン改変測定法
- 野生型と変異型の米におけるOsNDB2の遺伝子発現分析
主要な成果:
- JMJ720遺伝子は,米粒の大きさの重要なレギュラーとして特定されました.
- jmj720変異種は野生型の米と比較して 大きく粒子が出ていた.
- JMJ720はヒストンH3K9me2デメチラーゼとして機能し,OsNDB2発現を抑制し,より大きな粒子を発生させます.
- JMJ720が媒介するOsNDB2発現の減少は,粒子の大きさの増加と直接相関しています.
結論:
- JMJ720とヒストンのメチル化が関わる新しい表遺伝的メカニズムは 米粒の大きさを調節する.
- JMJ720は,OsNDB2の発現をエピジェネティックに調節することで粒子の大きさを制御します.
- JMJ720-OsNDB2経路をターゲットにすることで,より大きな穀物と収穫量を持つ大米を育成するための有望な道を示しています.
さらに関連する動画
関連する概念動画
Gene Regulation During Sporulation
77
Sporulation is a complex developmental process that allows certain Gram-positive bacteria, such as Bacillus subtilis and Clostridium species, to survive extreme environmental conditions. This process is tightly regulated by a series of signaling cascades and transcriptional controls, ensuring the formation of a highly resistant endospore.Sporulation is triggered by unfavorable conditions, such as nutrient depletion, and is governed by a phosphorelay system. One of the sensor kinases, such as...
77
Chromatin Structure Regulates pre-mRNA Processing
7.2K
In eukaryotic cells, nascent mRNA transcripts need to undergo many post-transcriptional modifications to reach the cell cytoplasm and translate into functional proteins. For a long time, transcription and pre-mRNA processing were considered two independent events that occur sequentially in the cell. However, it has now been well established that transcription and pre-mRNA processing are two simultaneous processes that are precisely regulated inside the cell.
The chromatin structure, especially...
The chromatin structure, especially...
7.2K
Position-effect Variegation
6.5K
In 1928, a German botanist Emil Heitz observed the moss nuclei with a DNA binding dye. He observed that while some chromatin regions decondense and spread out in the interphase nucleus, others do not. He termed them euchromatin and heterochromatin, respectively. He proposed that the heterochromatin regions reflect a functionally inactive state of the genome. It was later confirmed that heterochromatin is transcriptionally repressed, and euchromatin is transcriptionally active chromatin.
6.5K
Master Transcription Regulators
2.3K
2.3K
Chromatin Position Affects Gene Expression
23.7K
Chromatin is the massive complex of DNA and proteins packaged inside the nucleus. The complexity of chromatin folding and how it is packaged inside the nucleus greatly influences access to genetic information. Generally, the nucleus' periphery is considered transcriptionally repressive, while the cell's interior is considered a transcriptionally active area.
Topologically Associated Domains (TADs)
The 3-dimensional positioning of chromatin in the nucleus influences the...
Topologically Associated Domains (TADs)
The 3-dimensional positioning of chromatin in the nucleus influences the...
23.7K
Transgenic Plants
7.4K
Recombinant DNA technology called transgenesis is often used to add a foreign gene or remove a detrimental gene from an organism. Such genetically modified organisms are called transgenic organisms.
The first-ever transgenic plant was a tobacco plant developed in 1983 that showed resistance against the tobacco mosaic virus. Since then, many transgenic plants have been developed and commercialized for improving the agricultural, ornamental, and horticultural value of a crop plant. Transgenic...
The first-ever transgenic plant was a tobacco plant developed in 1983 that showed resistance against the tobacco mosaic virus. Since then, many transgenic plants have been developed and commercialized for improving the agricultural, ornamental, and horticultural value of a crop plant. Transgenic...
7.4K


