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デンドロビンAは胃がんを抑制する:統合された証拠によるメカニズムの洞察

Yonghao Fan1, Yan Chen2, Wenyan Lu2

  • 1Key Laboratory of Emergency and Trauma of Ministry of Education, Engineering Research Center for Hainan Biological Sample Resources of Major Diseases, the Hainan Branch of National Clinical Research Center for Cancer, the First Affiliated Hospital, Hainan Medical University, Haikou 571199, China; Department of General Medicine, West China Lecheng Hospital of Sichuan University, Boao 571400, China.

Phytomedicine : international journal of phytotherapy and phytopharmacology
|September 6, 2025
PubMed
まとめ

Dendrobium nobileの化合物であるデンドロビンAは,HSP90AB1 / CDK2 / PARP1を標的にし,P53/ PI3K-Akt経路を調節することにより,治療の可能性を示しています.

キーワード:
デンドロビンA胃がん分子ドッキングネットワーク薬理学P53シグナリングPI3KAkt経路についてWGCNA

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