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Updated: Sep 8, 2025

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神経変性疾患における標的型タンパク質分解の現在の傾向

Gulshan Kumar1, Vaibhav Thakur2, Satish Sardana1

  • 1Amity Institute of Pharmacy, Amity University Haryana, 122413, India.

European journal of medicinal chemistry
|September 6, 2025
PubMed
まとめ

標的型タンパク質分解 (TPD) は,有害な誤折りたたまれたタンパク質をクリアすることで,神経変性疾患 (ND) の治療の新たな方法を提供します. PROTACやLYTACのような新型TPD技術は,NDSにおける薬剤発見に有望です.

キーワード:
水性タグ付けLYTAC について神経変性プロタックタンパク質の分解

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