60歳以上のHIV/エイズの長期的傾向:グローバルと地域比較による多次元分解,1990-2021年
Yanhui Ma1, Weifang Tong2, Yi Liu3
1Department of Laboratory Medicine, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China; Faculty of Medical Laboratory Science, College of Health Science and Technology, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China.
Journal of infection and public health
|September 6, 2025
まとめ
世界的なHIV/AIDSの負担は高齢者の間で増加しており,感染者数も増加すると予測されています. この高齢化がもたらす課題に対処するには 緊急に年齢に配慮した戦略が必要です
科学分野:
- ゲロントロジー
- 流行病学について
- 公衆衛生
背景:
- 抗レトロウイルス治療はHIV/AIDSの生存率を向上させていますが,研究と政策はしばしばHIVに感染した高齢者を無視しています.
- この見落としは HIV感染者の高齢者層のケアに 大きなギャップを生み出しています
研究 の 目的:
- 1990年から2021年までの60歳以上の成人におけるHIV/エイズの世界,地域,および国の負担を評価する.
- HIV/AIDSの主要な指標を分析し,高齢者の将来の傾向を予測する.
- 高齢者のHIV/エイズ負担の変化の要因を特定する.
主な方法:
- 2021年グローバル・バード・オブ・ディジーズ・スタディのデータを活用した.
- トレンド予測のためのベイジアン年齢期間コホート (BAPC) モデリングを使用した.
- 負荷変化の要因を特定するために分解分析を行いました.
主要な成果:
- 全世界のHIV/AIDSの発生,流行,死亡率は高齢者 (2022-2035) で増加すると予測されており,絶対的な症例数は増加しています.
- 年齢基準の罹患率と死亡率は,1990年から2021年の間に有意に増加した (それぞれ580.76%と102.44%).
- 人口増加は,特に社会人口指数 (SDI) が高い地域では,発症率と死亡率の増加の主な要因として特定されました.
結論:
- 高齢者におけるHIV/AIDSの負担の増加は 人口高齢化と30年にわたる変化の影響を強調しています
- 罹患率,死亡率,障害調整寿命 (DALY) の増加により,年齢特有のHIV/エイズケア戦略の開発が求められています.
- 効果的な公衆衛生の介入には 老化中のPLHIVのユニークなニーズに対処することが不可欠です.
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