関連する実験動画

Updated: Sep 8, 2025

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
07:16

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission

Published on: August 16, 2018

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ヒトのGABAトランスポーター3の基板と阻害剤の結合

Hao Xu1, Yimin Zhang2, Qinru Bai3

  • 1Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China; Key Laboratory of Biomacromolecules (CAS), National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.

Structure (London, England : 1993)
|September 6, 2025
PubMed
まとめ

研究者はGABAトランスポーター3 (GAT3) の構造を明らかにし,GABAと薬SNAP-5114の結合を明らかにした. これは,GAT3を標的とした新しい治療の開発のための洞察を提供します.

キーワード:
GABAトランスポーターGAT3 についてスナップ-5114クリオ・エム構造

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