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Updated: Sep 8, 2025

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota
07:15

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Published on: July 31, 2019

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インスリン抵抗性における腸内微生物の中間レギュレータとしてのポータル静脈濃縮代謝産物

Vitor Rosetto Muñoz1, Francois Moreau1, Marion Soto1

  • 1Section of Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA.

Cell metabolism
|September 6, 2025
PubMed
まとめ

腸内微生物は,ポータルおよび周辺代謝産物を通してインスリン抵抗性に影響します. シトラコネートなどの特定の代謝物は,インスリン信号伝達を改善し,2型糖尿病のリスクを管理するのに役立ちます.

キーワード:
TCAサイクル糖尿病遺伝子調節腸内微生物群インスリンシグナルメサコネートメタボロミクス微生物メタゲノミクスポータルの循環

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