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Updated: Sep 8, 2025

Optimized Analysis of In Vivo and In Vitro Hepatic Steatosis
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PI3Kの潜在的な天然阻害剤であるサパノンAは,実験モデルにおける代謝機能障害に関連したステアト肝炎を緩和する

Xi Qiao1, Qian Li2, Ruiqi Fan2

  • 1Department of Endocrinology, First Hospital of Shanxi Medical University, Shanxi Medical University, Taiyuan 030001, China; Department of Pharmacology, School of Basic Medicine, Shanxi Medical University, Taiyuan 030001, China.

Biochemical pharmacology
|September 6, 2025
PubMed
まとめ

サパノンAは,代謝機能障害に関連した脂肪肝炎 (MASH) の治療に有望である. この天然化合物はPI3Kを阻害し,MASHモデルにおける肝損傷,炎症,および線維症を軽減します.

キーワード:
CMap についてマッシュ分子ダッキングネットワーク薬理学サパノンA

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