関連する実験動画

Updated: Sep 8, 2025

Studying Interactions between Myeloid Cells and CAR T Cells In Vitro and In Vivo
05:16

Studying Interactions between Myeloid Cells and CAR T Cells In Vitro and In Vivo

Published on: July 25, 2025

284

数学的モデルによると,現在のCARマクロファージの投与量は,低濃度の注入前腫瘍負荷に対して有効であるが,高濃度の腫瘍負荷に対して耐火性である

Shilian Xu1, Maoxuan Liu2

  • 1Department of Environment and Genetics, School of Agriculture, Biomedicine and Environment, La Trobe University, Bundoora, Australia; Department of Mathematics and Statistics, La Trobe University, Centre for Epidemiology and Biostatistics, Bundoora, Australia; Faculty of Biology, Technion-Israel Institute of Technology, Haifa, Israel.

Journal of theoretical biology
|September 6, 2025
PubMed
まとめ

化学抗原受容体 (CAR) - マクロファージ治療は,がん治療において有望である. 数学的モデリングは,最適な投与量と腫瘍負荷が有効なCARマクロファージ治療の結果にとって重要であることを示しています.

キーワード:
B細胞急性リンパ性白血病ビスタビリティCARマクロファージ投与スケジュール免疫療法輸液用量リンパ腫腫瘍負担

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