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Updated: Sep 8, 2025

Reverse Yeast Two-hybrid System to Identify Mammalian Nuclear Receptor Residues that Interact with Ligands and/or Antagonists
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Published on: November 15, 2013

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グルココルチコイド受容体は,NRF2媒介によるSLC7A11の発現を抑制する

Sarah E Lacher1, Jennifer Krznarich1, Daniel C Levings1

  • 1Department of Biomedical Sciences, University of Minnesota Medical School, Duluth, MN, 55812 USA.

Free radical biology & medicine
|September 6, 2025
PubMed
まとめ

グルココルチコイド受容体 (GR) は,NRF2調節要素に結合することによって,SLC7A11発現を直接抑制する. この発見は,抗酸化能力とグルタミン酸レベルを制御する新しいメカニズムを明らかにしています.

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