腸-脳相互作用の障害を持つ成人の回避性/制限性食物摂取障害 (ARFID) 症状の流行と負担:集団ベースの研究
Rosie Flack1, Grace Brownlow1, Helen Burton-Murray2
1Division of Clinical Medicine, School of Medicine and Population Health, University of Sheffield, UK; Academic Department of Gastroenterology, Sheffield Teaching Hospitals, Sheffield, UK.
Gastroenterology
|September 6, 2025
まとめ
腸-脳相互作用障害 (DGBI) は,一般人群において,回避性/制限性食物摂取障害 (ARFID) の症状と頻繁に関連している. この関連は,健康上の負担を増加させ,DGBI患者の定期的なARFIDスクリーニングを必要とします.
科学分野:
- 胃腸内科
- 精神科
- 公衆衛生
背景:
- 腸-脳相互作用障害 (DGBI) は,一般的な機能的胃腸障害である.
- 回避性/制限性食物摂取障害 (ARFID) の症状は,DGBIと共に発生することがあります.
- 以前の研究は専門病院に限られていた.
研究 の 目的:
- 大人の一般集団におけるDGBIとARFIDの関連性を評価する.
- DGBI の患者と患者でない人の間で ARFID の流行を決定する.
- DGBIとARFIDの同時発生に関連する健康上の負担を調査する.
主な方法:
- イギリスとアメリカでは2023年に人口ベースのインターネット調査が行われました.
- 参加者はDGBIのローマIV診断アンケートと9項目のARFIDスクリーン (NIAS) を記入しました.
- 収集されたデータには,人口統計,BMI,体質症状,心理的苦痛,生活の質,医療の使用が含まれています.
主要な成果:
- 4002人の参加者の42. 6%が少なくとも1つのDGBIと適合する症状を持っていた.
- ARFID陽性スクリーニングは,DGBI患者 (34. 6%) が,DGBI患者 (19. 4%) に比べて有意に高かった.
- 感染したDGBIの解剖学的領域の数とともにARFIDの存在が増加し,同時発生はより大きな健康負担をもたらしました.
結論:
- 陽性なARFIDスクリーンは,DGBIの患者で一般的です.
- ARFIDとDGBIの同時発生は,一般的な健康上の負担の増加と関連しています.
- 整合的な治療計画にインパクトを与えるために,DGBI患者の定期的なARFIDスクリーニングが推奨されます.
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