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Updated: Sep 8, 2025

Using Enzyme-based Biosensors to Measure Tonic and Phasic Glutamate in Alzheimer's Mouse Models
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グルタミン酸誘発性興奮毒性におけるGLT-1/EAAT2の神経保護作用

Yi Zhang1, Wen Liu1, Tao Huang1

  • 1Department of Rehabilitation Medicine, the First Affiliated Hospital of Nanchang University, Nanchang, China.

Behavioural brain research
|September 6, 2025
PubMed
まとめ

グルタミン酸トランスポーター1 (GLT-1) は脳の健康に不可欠であり,過剰なグルタミン酸を浄化することによって興奮毒性を予防します. GLT-1機能の強化は,様々な神経疾患の治療の可能性を提供します.

キーワード:
興奮毒性GLT-1/EAAT2についてミトコンドリア機能障害神経炎症神経学的障害神経保護酸化ストレス治療戦略

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