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Updated: Sep 8, 2025

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S100A4は,ポリプロイドの大型がん細胞の芽生えを促すことで,放射線誘発による腫瘍の再増殖を促進する

Ruyi Zhao1, Yanwei Song2, Jianzhu Xie2

  • 1Department of Vascular Surgery, Shanghai General Hospital of Nanjing Medical University, Shanghai, China.

Cancer letters
|September 6, 2025
PubMed
まとめ

ポリプロイド巨型がん細胞 (PGCC) は,放射線治療後の大腸がんの再増殖を促します. S100A4- ISG15経路を標的にすることで,PGCCの芽生えを抑制し,治療抵抗を克服し,放射線感受性を改善します.

キーワード:
デポリプロイド化ISG15 についてインターフェロンIシグナルポリプロイドの大型がん細胞 (PGCC)放射線耐性S100A4 について腫瘍の再生

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