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Updated: Sep 8, 2025

Ferritinophagy: Assessing the Selective Degradation of Iron by Autophagy in Human Fibroblasts
09:21

Ferritinophagy: Assessing the Selective Degradation of Iron by Autophagy in Human Fibroblasts

Published on: February 23, 2024

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TXNIPは,NCOA4媒介のフェリチノファギーによってフェロプトーシスを促進する

Pandian Nagakannan1, Md Imamul Islam2, Shakila Sultana2

  • 1Department of Physiology and Pathophysiology, University of Manitoba, Health Sciences Centre, Winnipeg, Canada; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.

Biochimica et biophysica acta. Molecular cell research
|September 6, 2025
PubMed
まとめ

チオレドキシン阻害タンパク質 (TXNIP) はフェロプトーシスを駆動し,これは病気に関与する細胞死経路です. TXNIPを阻害することは,フェロプトーシスを含む状態のための新しい治療戦略を提供することができる.

キーワード:
オートファジーエラスティングルタマートアイアン脂質過酸化リソソームミトコンドリアRSL3 について

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