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Updated: Sep 8, 2025

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癌およびそれ以上の病理的なERK1/2シグナリングをターゲットにする

Constanze Schanbacher1, Maria-Elisabeth Goebeler2, Brenda Gerull3

  • 1Institute of Pharmacology and Toxicology, University of Würzburg, 97078 Würzburg, Germany.

Trends in molecular medicine
|September 6, 2025
PubMed
まとめ

RAF-MEK-ERK1/2経路をターゲットにすることで 癌以外の病気の治療戦略が生まれます 癌薬の開発から得た教訓は,ERK1/2の調節不全を含むRASopatiesのような疾患の治療に役立つ.

キーワード:
ERK1/2MAPKラソパシー癌について心臓毒性阻害剤

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