妊娠中および産後期に連続した臓関節MRIによる,新生児の骨炎凝縮性硬化症の進化
Rosa Marie Kiil1, Ulrich Weber2, Anne Grethe Jurik1
1Department of Radiology, Aarhus University Hospital, Aarhus, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Annals of the rheumatic diseases
|September 6, 2025
まとめ
妊娠中および妊娠後,骨髄腫と脂肪の病変に関連して,軟骨下軟骨関節硬化症が深まります. より深い硬化症は骨炎凝縮症 (OCI) を示す可能性があります.
科学分野:
- 放射線科
- 整形外科
- リウマトロジ
背景:
- 軟骨関節 (SIJ) 硬化症はX線検査の結果である.
- 骨髄凝縮炎 (Osteitis condensans ilii,OCI) は,SIJの腹筋側を硬化させることを特徴とする良性疾患である.
- 妊娠はSIJの変化と関連しています.
研究 の 目的:
- 妊娠から産後12ヶ月までのサブコンドラルSIJ硬化症の進行を追跡する.
- 磁気共鳴画像 (MRI) の特徴を特定するために,OCIの前またはそれに伴います.
- SIJ硬化と分娩後の痛みを関連付けるため
主な方法:
- 妊娠中および産後3,6,12ヶ月で103人の初産の母親に一連のSIJMRIスキャンが行われました.
- 3人の読者は独立してサブコンドラル硬化症,骨髄腫 (BME),脂肪病変,侵食を評価した.
- 統計分析は,硬化症の進化とMRIの発見と痛みとの関連を調査した.
主要な成果:
- 産後12カ月で,下下腺硬化症の罹患率は20%から46%に増加し,深度も拡大した.
- 骨髄腫 (BME) は産後3ヶ月でピークに達し,脂肪の病変は後により一般的であった.
- 産後12ヶ月で8ミリメートル以上の硬化症は,BMEと脂肪の病変の発生率が高く,痛みとは無関係でした.
結論:
- 妊娠中のおよび妊娠後の進行性SIJ硬化症は,出産後のBMEおよび脂肪病変と関連しています.
- BMEは硬化症や脂肪病変の発生に先行する可能性があります.
- 重要なBMEと脂肪の病変を持つ硬化症の深さ ≥8mmは,放射線OCIのMRIバイオマーカーである可能性があります.
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