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Updated: Sep 8, 2025

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炎症性腸疾患における患者特有の規制ネットワークの再配線: 遺伝的ポリモルフィズムが受信信号を誘導し,疾患の発生に貢献する方法

Balazs Bohar1, John P Thomas1,2, Yufan Liu1

  • 1Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom.

Inflammatory bowel diseases
|September 7, 2025
PubMed
まとめ

炎症性腸疾患 (IBD) 遺伝的変異 細胞シグナリングを改造する 私たちの研究は これらの遺伝的変化が 転写因子結合にどのように影響し 遺伝子発現とIBDの発達に 影響を及ぼし 個別的な洞察を提供することを明らかにしています

キーワード:
クローン病遺伝子規制ネットワーク炎症性腸疾患信号経路シングルヌクレオチドポリモーフィズムシステムゲノミクス潰瘍性大腸炎

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