関連する実験動画

Updated: May 13, 2026

Visualizing the Node and Notochordal Plate In Gastrulating Mouse Embryos Using Scanning Electron Microscopy and Whole Mount Immunofluorescence
09:36

Visualizing the Node and Notochordal Plate In Gastrulating Mouse Embryos Using Scanning Electron Microscopy and Whole Mount Immunofluorescence

Published on: November 6, 2018

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マウスの早期臓器形成中の完全な胚のデジタル復元

Peng Xie1, Juan Shen2, Yi Yang3

  • 1Department of Cardiac Surgery, Jiangsu Provincial Key Laboratory of Critical Care Medicine, Zhongda Hospital, Key Laboratory of Developmental Genes and Human Disease, State Key Laboratory of Digital Medical Engineering, School of Biological Science and Medical Engineering, School of Life Science and Technology, Southeast University, Nanjing 210096, China; Coinnovation Center of Neuroregeneration, Nantong University, Nantong 226001, China.

Cell
|September 8, 2025
PubMed
まとめ

研究者らは,初期オルガノゲネシス中の遺伝子発現をマッピングするために,高解像度の"デジタル胚"を作成しました. このツールは 臓器形成と発達障害の理解に 重要な空間信号ネットワークを明らかにします

キーワード:
交差するシグナル通信デジタル胚早期の臓器形成オリジナルの決定領域単細胞3Dトランスクリプトーム心臓の新月

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Cleavage and Blastulation01:33

Cleavage and Blastulation

After a large-single-celled zygote is produced via fertilization, the process of cleavage occurs while zygotes travel through the uterine tube. Cleavage is a mitotic cell division that does not result in growth. With each round of successive cell division, daughter cells get increasingly smaller.
Gastrulation01:56

Gastrulation

Gastrulation establishes the three primary tissues of an embryo: the ectoderm, mesoderm, and endoderm. This developmental process relies on a series of intricate cellular movements, which in humans transforms a flat, “bilaminar disc” composed of two cell sheets into a three-tiered structure. In the resulting embryo, the endoderm serves as the bottom layer, and stacked directly above it is the intermediate mesoderm, and then the uppermost ectoderm. Respectively, these tissue strata will form...
Zygotic Development And Stem Cell Formation01:10

Zygotic Development And Stem Cell Formation

The development of all multicellular organisms starts with the fusion of haploid cells called sperm and egg to form a diploid zygote. A zygote is a totipotent cell that can develop into a complete organism. The zygote undergoes cell division or cleavage to form an 8-cell mass. Until this stage, the cells are spherical, loosely attached, and remain totipotent. Totipotent cells are capable of developing both the embryonic and the extraembryonic tissues. However, as they continue to divide, they...