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Updated: Jan 18, 2026

Antimicrobial Peptides Produced by Selective Pressure Incorporation of Non-canonical Amino Acids
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ノカルディシン生物合成における3-アミノ-3-カルボキシプロピルの構造的基礎

Yaojie Gao1,2, Masayuki Karasawa3, Zhiyang Quan4

  • 1Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo 113-0033, Japan.

Journal of the American Chemical Society
|September 8, 2025
PubMed
まとめ

S-アデノシル-l-メチオニンは,3-アミノ-3-カルボキシプロピル (3-ACP) ドナーとして酵素反応に作用する. この研究は,この生物学的過程の理解を深め,酵素NATによる3-ACP移転の構造的基礎とメカニズムを明らかにしています.

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