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Updated: Jan 18, 2026

Constructing Thioether/Vinyl Sulfide-tethered Helical Peptides Via Photo-induced Thiol-ene/yne Hydrothiolation
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Constructing Thioether/Vinyl Sulfide-tethered Helical Peptides Via Photo-induced Thiol-ene/yne Hydrothiolation

Published on: August 1, 2018

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ネイティブ・レジュード形成ペプチド連結のためのサイクルヒドロキシラミン:ウビキチンとティルゼパチドの合成

Jiling Han1, Kohtaro Hirao1, Toshiki Mikami1

  • 1Laboratory for Organic Chemistry, Department of Chemistry and Applied Biosciences, ETH Zürich, Zürich 8093, Switzerland.

Journal of the American Chemical Society
|September 11, 2025
PubMed
まとめ

新しいサイクルダイペプチド派生ヒドロキシラミンブロックは,α-ケトアシド-ヒドロキシラミン (KAHA) 化学を用いてネイティブペプチド結合を可能にします. チルゼパチドのような 治療用分子を含めた複雑なペプチドの合成を 促進します

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