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Updated: May 4, 2026

Development and Validation of an Ultrasensitive Single Molecule Array Digital Enzyme-linked Immunosorbent Assay for Human Interferon-α
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Development and Validation of an Ultrasensitive Single Molecule Array Digital Enzyme-linked Immunosorbent Assay for Human Interferon-α

Published on: June 14, 2018

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大分子ダイアミドベンジミダゾール結合体は,インターフェロン遺伝子の刺激剤を活性化することができる

Karan Arora1, Taylor L Sheehy2, Jacob A Schulman2

  • 1Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, Tennessee 37212, United States.

Journal of the American Chemical Society
|September 12, 2025
PubMed
まとめ

二次性アミドベンジミダゾール (diABZI) の安定ポリマー結合体は,小分子と同様にインターフェロン遺伝子刺激剤 (STING) を活性化します. これらのマクロ分子結合体は,新しい治療設計戦略を示唆する,in vivoの有望な抗腫瘍活性を示しています.

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