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Updated: Jan 17, 2026

A Rat Carotid Artery Pressure-Controlled Segmental Balloon Injury with Periadventitial Therapeutic Application
06:53

A Rat Carotid Artery Pressure-Controlled Segmental Balloon Injury with Periadventitial Therapeutic Application

Published on: July 9, 2020

5.5K

TAX1BP3はSUMOYlated核細胞質シャトルタンパク質であり,血管新生性高血症から保護する

Hanyan Yang1,2, Yulong Zhong3, Wenjie Guo1,2

  • 1Department of Cardiology, Laboratory of Heart Center, Translational Medicine Research Center, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China (H.Y., Wenjie Guo, Wenjing Guo, B.C., Z.L., X.C., J.Y., Z.Z., S.A., C.L.).

Circulation
|September 16, 2025
PubMed
まとめ

血管の滑らかな筋肉細胞 (VSMC) の機能に不可欠なTAX1BP3タンパク質は,その核の局所化を調節するためにSUMOylatedされています. このタンパク質は,YAP-TEADとの相互作用によってVSMCの増殖を抑制することで,ネオインティマル・ハイパープラジアを予防します.

キーワード:
PDZドメイン動脈疾患細胞増殖血管の損傷血管の滑らかな筋肉

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