菌血症を伴う腸チフスと肺結核の稀な同時発症

Shuhua Guo1, Minghsun Liu2

  • 1Southern California Hospital Culver City, Culver City, California; Coast Plaza Hospital, Norwalk, California, USA.

Archives of clinical and biomedical research
|September 17, 2025
PubMed

この症例報告では、82歳の女性に認められた腸チフスと肺結核(TB)の併発という稀な提示について述べる。患者は失神と脱水症状で入院し、当初は肺炎と尿路感染症(UTI)が疑われた。尿および血液培養によりグラム陰性桿菌が速やかに検出され、CT画像では両側上葉および左下葉に空洞性病変が認められた。このグラム陰性桿菌は、以下として同定された。Salmonella enterica subspecies enterica Typhi、および喀痰の抗酸菌(AFB)PCRおよび培養により、以下の存在が確認されました。Mycobacterium tuberculosis複雑な症例であった。患者は腸チフスと肺結核の両方に対して治療を受けた。この稀な症例は、単一の疾患プロセスが複数の症状の原因となっているのか(オッカムの剃刀)、あるいは複数の疾患が同時に患者に影響を及ぼしているのか(ヒッカムの格言)を区別するという臨床上の課題を浮き彫りにしている。本例では、2つの異なる感染症によって複雑な臨床像が説明された。腸チフスが先に診断されており、稀に肺膿瘍を伴うことがあるが、空洞性肺病変は肺結核でより一般的に見られる。本症例は、複雑な臨床シナリオにおいて、複数の同時感染を考慮することの重要性を強調している。

キーワード:
腸チフス結核

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