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Updated: Jan 17, 2026

Simultaneous Mapping and Quantitation of Ribonucleotides in Human Mitochondrial DNA
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リボヌクレオチドがミトコンドリアDNAに組み込まれると炎症が起こります

Amir Bahat1, Dusanka Milenkovic1, Eileen Cors1

  • 1Max Planck Institute for Biology of Ageing, Cologne, Germany.

Nature
|September 24, 2025
PubMed
まとめ

代謝失調によりリボヌクレオチドがミトコンドリアDNA (mtDNA) に入り,炎症を引き起こします. デオキシリボヌクレオシドの供給は,この年齢に関連する炎症反応と老化に関連した分泌現象型 (SASP) を減らすことができます.

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