関連する実験動画

Updated: Jan 15, 2026

Targeted Plasma Membrane Delivery of a Hydrophobic Cargo Encapsulated in a Liquid Crystal Nanoparticle Carrier
10:16

Targeted Plasma Membrane Delivery of a Hydrophobic Cargo Encapsulated in a Liquid Crystal Nanoparticle Carrier

Published on: February 8, 2017

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細胞外標的タンパク質劣化剤-薬剤結合剤をハイジャックし,薬剤の投与を強化する

Fangzhu Zhao1, Yan Wu1, Kaitlin Schaefer1

  • 1Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California 94158, United States.

Journal of the American Chemical Society
|October 15, 2025
PubMed
まとめ

退化剤薬結合剤 (DDC) は,抗体薬結合剤と細胞外標的タンパク質の分解を組み合わせることで,がん治療を強化する. DDCは溶解体伝達と細胞毒性を改善し,次世代治療の選択肢を提供します.

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Drugs target macromolecules to modify ongoing cellular processes. Primary drug targets include receptors, ion channels, transporters, and enzymes.
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