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Updated: Jan 14, 2026

Identification of Specific Sensory Neuron Populations for Study of Expressed Ion Channels
11:34

Identification of Specific Sensory Neuron Populations for Study of Expressed Ion Channels

Published on: December 24, 2013

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ニューロン発射を抑制する電圧ゲートアニオンチャネル

Chen Zhou1, Huican Li1, Jiaxing Wang2

  • 1School of Life Sciences, Fudan University, Shanghai 200438, China; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou 310024, Zhejiang, China; State Key Laboratory of Gene Expression, Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences and Research Center for Industries of the Future, Westlake University, Hangzhou 310024, Zhejiang, China; Institute of Biology, Westlake Institute for Advanced Study, Hangzhou 310024, Zhejiang, China.

Cell
|October 17, 2025
PubMed
まとめ

科学者は電圧に反応する 新しい電圧ゲートアニオンチャネル (dVGAC) を設計しました これらの設計されたタンパク質チャネルは 電圧に依存するアニオン電流を示し ニューロンの活動を制御するために調整でき センサーの開発を進めるのです

キーワード:
クロライドチャンネル形状の変化冷凍電子顕微鏡de novo タンパク質のデザインディープラーニングイオン選択性ニューロンの発射トランスメブランタンパク質調節可能なイオン選択性と電圧感度ボルトゲートイオンチャネル

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