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エントロパトゲン菌はROCK駆動の上皮細胞挤出を回避する

Giovanni Luchetti1, Marin V Miner2, Rachael M Peterson2

  • 1Department of Discovery Oncology, Genentech, South San Francisco, CA, USA. luchettg@gene.com.

Nature
|October 22, 2025
PubMed
まとめ

エシェリキア・コライの毒性因子NleLは,ROCK1/2を分解することによって,腸内上皮細胞の挤出を防ぐ. このメカニズムにより 病原体は宿主の防御を回避し 宿主-病原体の軍拡競争を強調します

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