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Updated: Jan 14, 2026

Constructing Thioether/Vinyl Sulfide-tethered Helical Peptides Via Photo-induced Thiol-ene/yne Hydrothiolation
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Constructing Thioether/Vinyl Sulfide-tethered Helical Peptides Via Photo-induced Thiol-ene/yne Hydrothiolation

Published on: August 1, 2018

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チオエステラゼと半合成ポリケチドの反応による選択性傾向の確立

Zachary C Litman1, Yuanhuang Chen1, David H Sherman1,2

  • 1University of Michigan, Life Sciences Institute, Ann Arbor, Michigan 48109, United States.

Journal of the American Chemical Society
|October 24, 2025
PubMed
まとめ

この研究では,ポリケチド合成の鍵となる酵素であるチオエステラス (TEs) を研究しています. ミュータントのTEsはより広範な活動を示し,新しい治療的天然製品の発見の可能性を広げています.

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