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Updated: Jan 14, 2026

Monitoring the Cancer-Immunity Cycle and Exploring Tumor Microenvironment Dynamics
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がん細胞は 免疫監視から逃れるために 臓器間の神経免疫回路を利用します

Yu Zhang1, Yibo Guo2, Zheqi Liu3

  • 1Department of Oral and Maxillofacial Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China; Department of Hepatobiliary Surgery and Liver Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Shanghai 200032, China; Department of Stomatology, Zhongshan Hospital, Fudan University, Shanghai 200032, China.

Cell
|October 25, 2025
PubMed
まとめ

ガン細胞は 抗腫瘍免疫を抑制する 痛みの経路を活性化することで 免疫監視から逃れるのです この神経免疫回路をターゲットにすることで 免疫機能が回復し 免疫療法の効果が向上します

キーワード:
CGRP についてHNSCC についてTAM についてカルシトニン遺伝子関連ペプチドガン免疫学がん神経科学頭と首の状細胞癌免疫チェックポイントの封鎖リンパ節メラノーマノシセプティブニューロン腫瘍の微小環境腫瘍関連マクロファージ

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